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Implantable devices: small chips, big future

Implantable devices: small chips, big future

Drugs seem to be the first choice for the treatment of diseases. People have been fantasizing that if one day there is an implantable device that allows patients to no longer rely on drugs, that would be ideal.
Now, dreams are coming true. Recently, at the annual forum lecture British Academy of Medical Sciences, New York Feinstein institute director Professor Kevin Tracy said, the researchers instead of chemical drugs in the electrode for nerve stimulation has taken the first step.
The word "implantation" has been widely used in medicine, and it is based on the rescue of life and the repair of disabilities, such as pacemakers, brain stimulators, and cochlear implants. These mature medical technologies have been widely used in real life.
As early as 4 years ago, 3 year old Grayson Klemp had accepted the nation's first children's auditory brainstem implant surgery, the first time I heard the voice; in 2008, when the other chip implanted into the retina after the Tejo, at the age of 40, his first time in 10 years to see and identify some of the objects, not only read the print the letter, also recognize their loved ones.
Almost all cancer patients are afraid of opioids, and do not want to rely on it. In this regard, British scientists announced that they are developing a medical implantable devices, doctors will be able to track the growth of cancer in real time, how many drugs need to be delivered, where will be more targeted. It has a strong appeal for doctors and patients.
Cardiovascular diseases, diabetes, cancer, chronic respiratory diseases and other common chronic diseases have become the main cause of death. Because the chronic disease course is stubborn, the treatment depends on the long-term medication, which brings great inconvenience to the patient's life. How to get rid of the pain caused by long-term medication is a goal that scientists all over the world have been trying to develop. British pharmaceutical giant GlaxoSmithKline scientists have announced that in the next few years they will develop a micro implantable device that can treat chronic diseases. Once the device is developed, it will be a major breakthrough in the treatment of chronic diseases, and even allow patients to gradually get rid of drug dependence. It can be said that the application of these technologies in the field of chronic disease treatment is the future development trend of medical and health fields.
Most of the patients with Parkinson's disease are treated with drugs. In the late 60s of the last century, doctors were able to control the tremor by implanting electrodes in the brain to avoid the effects of long-term medication.
Deep brain stimulation is called "brain pacemaker", and it is a typical representative of the top scientific and technological applications in clinic. In 1995, the first generation of brain pacemakers developed by Medtronic Inc was put into clinical trials for the treatment of essential tremor and Parkinson tremor. Soon, as a new therapeutic approach, brain pacemakers are popular around the world. At the end of the 90s of last century, China began to introduce this technology, but the exclusive monopoly of the United States on the technology, resulting in high equipment prices, slow clinical promotion.
In support of the Ministry of science, Tsinghua University, Pinchi medical research team has developed a single channel, dual channel and rechargeable series of brain pacemaker, succeeded in breaking the monopoly of American technology. According to the Department of Neurosurgery of Beijing Tiantan Hospital professor Zhang Jianguo introduction, product localization neural control technology, not only greatly reduced in price, more technically reflect the advantage of remote control and frequency stimulation, 3.0T magnetic compatibility a innovation has been at the forefront of the world.
The existing brain pacemaker is not and high magnetic field scanning good compatibility, but the Tsinghua University director of the National Engineering Laboratory of Neural Control Technology Professor Li Luming has revealed that the team has invented a new electrode structure of carbon nano materials based on thin film package. This means that in the future, in the nuclear device, Tsinghua brain pacemaker can work properly, patients can be assured to do nuclear magnetic resonance examination. At present, this product is in clinical trial stage.
Chinese researchers not only do something about the brain, but also show their talents in the artificial heart. Recently, good news came from No.3 Hospital of Peking University, exciting. The "artificial heart" created by China's own research and development will break the monopoly of the western countries, and enable more Chinese people to accept the treatment so as to obtain the continuation of life.
Implantable equipment than wearable devices more convenient to carry, but another problem, is also the biggest problem is that disassembly has become extremely inconvenient, because both the battery into the body, or frequently these devices take energy from the body is not realistic. Whether we can solve this problem will determine whether the industry can develop healthily.
To address this problem, the research team at Draper lab in Massachusetts developed a biodegradable battery. As long as it is implanted inside the body, energy can be generated, and it can be transported to where it is needed, and then it can melt automatically. The invention undoubtedly advances the process of implantable intelligent devices.
Coincidentally, a group of researchers design at the University of California in Losangeles and University of Connecticut, by the human protein layered graphene electrode composed of "biological super capacitor energy storage system model, can make implantable medical devices no longer rely on batteries for energy. Other studies include the use of glucose in the body to provide power for implantable devices. Potato batteries, for example, are small, but more advanced.
Foreign countries have new research results, China will not lag behind. Recently, Fudan University has developed a lightweight generator that can implant human veins. It is reported that the generator is based on aligned carbon nanotubes wrapped around the polymer core, and the fibrous fluid nanofluids are responsible for the relative movement, thereby obtaining the gradient force of blood flow through the fiber layering. Although the technology is still in its early stages, they have implanted the device in frogs, and the results are ideal. Because of the high safety and security of the generator, it will be used in clinic in the future and contribute a lot to the technology of implanting medical equipment.
After years of research, industry experts generally believe that the implantable device is feasible, but due to the influence of surgical level and individual differences, for implantable electronic devices, any medical equipment can guarantee the safety of 100%.
According to experts, the Chinese Academy of Sciences Shenzhen Institute of advanced technology of medical chip design studio, the implantable device is a research domain of interdisciplinary, involving biomedical engineering, microelectronics, medical experts, all aspects of the need to work to solve the chip size, the battery life is short, biocompatibility and immune rejection problems. It is clear that implantable devices are safe in the normal range of use and safety".
With the development of implantable medical device technology, more and more fields will be supported. Although its safety will be widely questioned in the short term, we can still believe that these technologies and equipment will become an important part of clinical medicine in the future.